prion proteins การใช้

• Prusiner warned that prion proteins could jump from one species to another.
• The prion proteins that cause the disease are microscopic and extremely resilient,
• Similarly, removing the prion domain from a fungal prion protein inhibits prionogenesis.
• The putative infectious agent is the host-encoded prion protein, PrP.
• It acts as a receptor for prion proteins too.
• These mutations cause the cell to make prion proteins with an abnormal structure.
• Immunohistochemistry can be used to demonstrate prion protein accumulation.
• Normal prion protein is produced by a gene that is widely found in nature.
• Gambetti and his colleagues found no evidence of prion proteins after the enzyme tests.
• Some scientists believe the prion protein itself is the primary cause of the disease.
• The researchers used a laboratory test that identifies different chemical variants of prion proteins.
• From 8, 318 samples studied, one showed traces of the prion protein.
• Misshapen prion proteins carry the disease between individuals and cause deterioration of the brain.
• There is also experimental evidence for cross-seeding between prion protein and A?.
• Then they mixed it with unlabeled prion protein isolated from scrapie-infected hamster brains.
• First, the hypothesis holds, the prions touch normal prion proteins in the brain.
• It is marked by prion proteins that eventually turn the brain into a spongy mess.
• Specifically, this is determined by the genes coding for the naturally occurring prion proteins.
• In animal studies, they found that the laminin receptor increased along with infectious prion proteins.
• The old and new prion proteins each latch onto good proteins, and the process continues.